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| |
Women
|
Men
|
|---|
|
No CV events
|
CV events
|
p-value
|
No CV events
|
CV events
|
p-value
|
|---|
|
(n = 177)
|
(n = 22)
|
(n = 112)
|
(n = 16)
|
|---|
|
Age (years)
|
68.7 ± 8
|
69 ± 7
|
0.90
|
69 ± 8
|
72 ± 9
|
0.29
|
|
Caucasian (n, %)
|
130 (73%)
|
15 (68%)
|
0.36
|
86 (77%)
|
15 (94%)
|
0.34
|
|
African-American (n, %)
|
4 (24%)
|
6 (28%)
|
–
|
22 (20%)
|
1 (6%)
|
–
|
|
Body Mass Index (kg/m2)
|
31 ± 6
|
32 ± 6
|
0.26
|
29 ± 5
|
30 ± 7
|
0.53
|
|
Height (cm)
|
162 ± 7
|
164 ± 8
|
0.26
|
175 ± 8
|
175 ± 9
|
0.98
|
|
Weight (kg)
|
81 ± 18
|
89 ± 18
|
0.12
|
91 ± 17
|
95 ± 16
|
0.55
|
|
Total Cholesterol (mg/dL)
|
163 ± 46
|
172 ± 67
|
0.59
|
143 ± 36
|
151 ± 40
|
0.59
|
|
High Density Lipoprotein Cholesterol (mg/dL)
|
51 ± 14
|
49 ± 16
|
0.65
|
42 ± 14
|
41 ± 11
|
0.80
|
|
Hypertension, n (%)
|
168 (95%)
|
21 (95%)
|
0.91
|
102 (92%)
|
16 (100%)
|
0.09
|
|
Transient Ischemic Attack /Stroke, n (%)
|
6 (3%)
|
1 (5%)
|
0.76
|
9 (8%)
|
3 (18%)
|
0.21
|
|
Hypercholesterolemia, n (%)
|
128 (72%)
|
12 (55%)
|
0.09
|
68 (61%)
|
9 (57%)
|
0.73
|
|
Current smoker, n (%)
|
7 (4%)
|
2 (9%)
|
0.32
|
4 (4%)
|
1 (6%)
|
0.62
|
|
Diabetes, n (%)
|
64 (36%)
|
12 (54%)
|
0.09
|
50 (45%)
|
6 (38%)
|
0.59
|
|
Estimated Glomerular Filtration Rate (mL/min/1.73 m2)
|
58 ± 6
|
57 ± 9
|
0.58
|
58 ± 5
|
58 ± 4
|
0.99
|
|
Aspirin
|
109 (71%)
|
13 (62%)
|
0.6
|
84 (73%)
|
7 (53%)
|
0.41
|
|
Angiotensin Converting Enzyme Inhibitor
|
72 (41%)
|
6 (28%)
|
0.21
|
54 (48%)
|
8 (50%)
|
0.89
|
|
Beta Blocker
|
60 (35%)
|
7 (64%)
|
0.83
|
28 (25%)
|
3 (19%)
|
0.57
|
|
Diuretic
|
109 (62%)
|
13 (59%)
|
0.82
|
64 (57%)
|
9 (56%)
|
0.94
|
|
Angiotensin Receptor Blocker
|
65 (36%)
|
10 (45%)
|
0.43
|
27 (24%)
|
3 (18%)
|
0.62
|
|
Statin
|
129 (73%)
|
13 (59%)
|
0.19
|
82 (78%)
|
12 (75%)
|
0.78
|
|
Aldosterone antagonist
|
5 (3%)
|
1 (5%)
|
0.67
|
1 (1%)
|
0 (0%)
|
0.61
|
|
Calcium Channel Blocker
|
44 (25%)
|
9 (41%)
|
0.12
|
37 (33%)
|
6 (37%)
|
0.74
|
- Baseline demographics and clinical characteristics stratified by gender. Mean ± Standard Deviation or number (percent). A p-value < 0.05 indicates statistical significance