Loss of base-to-apex circumferential strain gradient assessed by cardiovascular magnetic resonance in Fabry disease: relationship to T1 mapping, late gadolinium enhancement and hypertrophy

Table 3 Correlation of myocardial strain values with mass, late gadolinium enhancement and T1 mapping values among patients with Fabry disease

	Global Longitudinal Strain (GLS)		Global Circumferential Strain (GCS)		Base-to-apex Longitudinal Strain Gradient		Base-to-apex Circumferential Strain Gradient
	r-value	p-value	r-value	p-value	r-value	p-value	r-value	p-value
LVMi (g/m²)	0.375	0.02	0.426	0.01	−0.101	0.60	−0.255	0.13
LGE (%)	0.508	0.002	0.298	0.08	−0.097	0.61	−0.089	0.61
Native T1 (ms)	0.112	0.51	−0.085	0.62	−0.006	0.98	−0.243	0.15
ECV (%)	−0.206	0.23	−0.250	0.14	−0.071	0.71	−0.265	0.12

Correlation was assessed using Spearman correlation. ECV extracellular volume, GCS global circumferential strain, GLS global longitudinal strain, LGE late gadolinium enhancement, LVMi left ventricular mass indexed to body surface area

ISSN: 1532-429X