You are viewing the site in preview mode
Skip to main content
|
Variable
|
Healthy subjects (n = 100)
|
HCM (n = 359)
|
P
|
HCMR Patients without combined outcome (n = 300)
|
HCM Patients with combined outcome (n = 59)
|
P
|
HCM Patients with LA diameter > 41 mm (n = 135)
|
HCM Patients with LA diameter ≤ 41 mm (n = 224)
|
P
|
|---|
|
Clinical data
|
|
Age, years
|
47 (36,66)
|
49 (39,60)
|
0.746
|
48 (36,55)
|
60 (49,69)
|
< 0.001*
|
52.3 ± 13.3
|
45.2 ± 17.3
|
< 0.001*
|
|
Male gender, n (%)
|
43 (43.0)
|
198 (55.2)
|
0.031*
|
171 (57.0)
|
27 (45.7)
|
0.113
|
64 (47.4)
|
134 (59.8)
|
0.022
|
|
BMI (kg/m2)
|
22.7 (20.7,24.3)
|
23.7 (21.5,25.6)
|
0.004*
|
23.7 (21.5,25.5)
|
23.6 (21.3,25.8)
|
0.754
|
24.2 (22.2,26.2)
|
23.3 (20.8,25.4)
|
0.001*
|
|
BSA (m2)
|
1.6 ± 0.2
|
1.7 ± 0.2
|
< 0.001*
|
1.7 ± 0.2
|
1.6 ± 0.2
|
0.033*
|
1.7 (1.6,1.8)
|
1.7 (1.5,1.8)
|
0.316
|
|
Heart rate (beat/minute)
|
72 (66,78)
|
73 (65,77)
|
0.654
|
73 (66,76)
|
71 (63,78)
|
0.431
|
73 (65,80)
|
73 (66,75)
|
0.164
|
|
Diabetes mellitus, n (%)
|
–
|
24 (6.7)
|
–
|
20 (6.7)
|
4 (6.8)
|
1.000
|
12 (8.9)
|
12 (5.4)
|
0.194
|
|
Hypertension, n (%)
|
–
|
82 (22.8)
|
–
|
62 (20.7)
|
20 (33.9)
|
0.027*
|
36 (26.7)
|
46 (20.5)
|
0.180
|
|
Obstructive HCM, n (%)
|
–
|
137 (38.2)
|
–
|
103 (34.3)
|
34 (57.6)
|
0.001*
|
67 (49.6)
|
70 (31.3)
|
0.001*
|
|
Family history of SCD, n (%)
|
–
|
49 (13.6)
|
–
|
39 (13.0)
|
10 (16.9)
|
0.419
|
18 (13.3)
|
31 (13.8)
|
0.892
|
|
History of syncope, n (%)
|
–
|
65 (18.1)
|
–
|
50 (16.7)
|
15 (25.4)
|
0.110
|
24 (17.8)
|
41 (18.3)
|
0.900
|
|
CAD, n (%)
|
–
|
27 (7.5)
|
–
|
21 (7.0)
|
6 (10.2)
|
0.566
|
15 (11.1)
|
12 (5.4)
|
0.045*
|
|
Cardiac medications
|
|
β blocker, n (%)
|
–
|
239 (66.6)
|
–
|
194 (64.7)
|
45 (76.3)
|
0.084
|
102 (75.6)
|
137 (61.2)
|
0.005*
|
- BMI body mass index, BSA body surface area, CAD coronary artery disease, HCM hypertrophic cardiomyopathy, SCD sudden cardiac death
- *p < 0.05; Data are expressed as mean ± SD, mean with 25th–75th percentiles in parentheses, or as a percentage for categorical variables
