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MACE
|
Cardiovascular mortality
|
|---|
|
Hazard ratio (95% CI)
|
p value
|
Hazard ratio (95% CI)
|
p value
|
|---|
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Age
|
1.04 (1.02–1.05)
|
< 0.001
|
1.06 (1.04–1.08)
|
< 0.001
|
|
Male
|
1.56 (1.14–2.14)
|
0.006
|
1.77 (1.21–2.60)
|
0.003
|
|
BMI
|
1.04 (0.98–1.09)
|
0.123
|
0.96 (0.90–1.03)
|
0.282
|
|
Hypertension
|
1.22 (1.03–1.60)
|
0.033
|
1.18 (0.97–1.57)
|
0.077
|
|
Diabetes mellitus
|
1.35 (1.04–1.77)
|
0.041
|
1.59 (1.14–2.23)
|
0.006
|
|
Dyslipidemia
|
1.41 (1.05–1.89)
|
0.022
|
1.55 (1.09–2.20)
|
0.014
|
|
Smoking
|
1.02 (0.77–1.36)
|
0.757
|
1.03 (0.79–1.40)
|
0.675
|
|
Family history of CAD
|
1.01 (0.74–1.38)
|
0.937
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1.05 (0.73–1.50)
|
0.810
|
|
Known CAD
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1.30 (1.01–1.69)
|
0.043
|
1.21 (0.93–1.71)
|
0.122
|
|
Known MI
|
0.80 (0.57–1.15)
|
0.222
|
0.82 (0.53–1.26)
|
0.361
|
|
Peripheral atheroma
|
1.35 (0.84–2.17)
|
0.212
|
1.59 (0.94–2.67)
|
0.082
|
|
Ischemic stroke
|
1.03 (0.53–2.01)
|
0.936
|
0.90 (0.39–2.03)
|
0.793
|
|
History of hospitalization for HF
|
1.35 (0.69–2.64)
|
0.376
|
1.48 (0.69–3.17)
|
0.311
|
|
Symptomatic angina
|
1.63 (0.83–3.22)
|
0.16
|
0.92 (0.50–1.71)
|
0.88
|
|
Dyspnea
|
0.91 (0.47–1.73)
|
0.77
|
0.78 (0.47–1.30)
|
0.35
|
|
Ten-year risk for fatal CAD (modified SCORE project)
|
1.22 (1.08–1.80)
|
< 0.001
|
1.29 (1.10–1.83)
|
< 0.001
|
|
Presence of inducible ischemia
|
2.88 (2.18–3.81)
|
< 0.001
|
2.44 (1.75–3.40)
|
< 0.001
|
|
Number of segments of inducible ischemia
|
1.61 (1.51–1.72)
|
< 0.001
|
1.55 (1.43–1.67)
|
< 0.001
|
|
Presence of LGE
|
1.46 (1.16–1.89)
|
< 0.001
|
1.38 (1.06–1.77)
|
0.031
|
|
Number of segments of LGE
|
1.40 (1.30–1.52)
|
< 0.001
|
1.33 (1.21–1.45)
|
< 0.001
|
|
LVEFa
|
0.85 (0.79–0.91)
|
< 0.001
|
0.92 (0.84–0.98)
|
0.024
|
|
LV end-diastolic volume indexa
|
1.07 (1.04–1.10)
|
< 0.001
|
1.03 (0.90–1.37)
|
0.315
|
|
LV end-systolic volume indexa
|
1.09 (1.05–1.12)
|
< 0.001
|
1.05 (0.92–1.42)
|
0.221
|
|
RV ejection fraction
|
0.99 (0.80–1.23)
|
0.45
|
1.09 (0.81–1.52)
|
0.72
|
|
CMR-related coronary revascularization
|
2.43 (1.83–3.22)
|
< 0.001
|
2.04 (1.46–2.86)
|
< 0.001
|
- Bold empasis means that the P value has reached statistical significance, with 2-tailed P value < 0.05
- BMI body mass index, CAD coronary artery disease, CI confidence interval, CMR cardiac magnetic resonance, HF heart failure, LGE late gadolinium enhancement, LV left ventricle, LVEF left ventricular ejection fraction, MACE major adverse cardiac events, MI myocardial infarction, RV right ventricle
- aIncrement of 10 units
- bDefined by a coronary revascularisation performed within 90 days after the stress CMR examination
